North Jersey Section of the ACS

Welcome to the North Jersey ACS Drug Metabolism Discussion Group

Our mission: We are dedicated to fostering a continued discussion on the scientific advances in drug metabolism among the industrial and academic community. We sponsor multiple meetings each year at which world renowned scientists give presentations. The format of these meetings range from dinner presentations and mini-symposiums to our annual 1-2 day fall symposium.

[ Upcoming Meeting | Past Meetings | Steering Committee ]

Oct 2009  |  Apr 2009  ]


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2006 Fall Symposium and Vendor Exhibition

October 14, 2009 – Fall Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Transporters, Current Industry Practices, and Biologics”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

October 14, 2009
8:00 am – 3:30 pm

Program

Transporters, Current Industry Practices, and Biologics

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

8:50 a.m.

Introductory Remarks

Dr. Philip Krieter, Chair, NJ-DMDG

9:00 a.m.

The Challenges of Designing Cyclic Prodrugs of Opioid Peptides that Permeate the Intestinal Mucosa and the Blood-Brain Barrier

Dr. Ron Borchardt, Solon E. Summerfield Distinguished Professor, Department of Pharmaceutical Chemistry, School of Pharmacy,  University of Kansas
[ slides ]

9:50 a.m.

In Vitro and In Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of American Perspective

Dr. Gondi Kumar, Senior Director, Department of Drug Metabolism and Pharmacokinetics, Celgene Corporation
[ slides ]

10:45 a.m.

Vendor Exhibit & Coffee Break

11:15 a.m.

Inactivation Studies for Predicting Drug-Drug Interactions. Pharmaceutical Industry Recommendations and Recent Observations

Dr. R. Scott Obach, Senior Research Fellow, Biotransformation Group, Pharmacokinetics, Dynamics and Drug Metabolism Department, Pfizer, Inc.
[ slides ]

12:00 Noon

Lunch & Vendor Exhibit

1:30 p.m.

Pharmacokinetic Based Drug-Drug Interactions of Biologicals. Science and Development Strategies

Dr. Frank-Peter Theil, Associate Director, Genentech, Inc.
[ slides ]

2:15 p.m.

Vendor Exhibit & Coffee Break

2:45 p.m.

PK/PD Study Strategies for Biopharmaceuticals: Is Bigger Better?

Dr. Sharon A. Baughman, Biotechnology Consulting
[ slides ]

3:30 p.m.

Program Closure

 

 

Registration:

Pre-registration fee is $125 (by Oct 7, 2009).

Registration is free for students (with proper identification).

Registration fee at the door is $150 (Checks only).

        Please plan to pre-register as a group, coordinated by a member of the NJACS DMDG steering committee from your organization (see list below).

        If you have no DMDG member at your company, please contact Phil Krieter () for registration.

        Payments by personal or company checks.  Sorry, credit cards are not accepted. 

        Checks should be made payable to: NJ Drug Metabolism Discussion Group. 

 

Exhibitors:

Please contact Karen Dingley () for information concerning exhibits

 

Directions to the Somerset Crowne Plaza Hotel:

110 Davidson Avenue,
Somerset, NJ
Phone: 732-560-0500
[ website ]

 

From the New Jersey Turnpike:

Exit 10 to Interstate 287 North.  Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook).  Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)

 

From New York City:

Lincoln Tunnel to N.J. Turnpike South.  Follow N.J. Turnpike directions mentioned above.

 

From Route 287:

If traveling north:

Exit 10 (527 New Brunswick-South Bound Brook).  Follow sign towards Bound Brook, to light make left (Davidson Ave.)

If traveling south:

Exit 10 (527 New Brunswick).  Left on Easton Ave., to light, make left (Davidson Ave).

 

From Newark Airport

Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.

 


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April 29, 2009 – Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Current Topics in Drug Metabolism and Pharmacokinetics: Biologics and Transporters – What's New?”

Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

April 29, 2009
8:45 am – 3:30 pm

Slides from the talks

  1. Imaging Techniques and Pharmacokinetic Modeling/Simulation: Useful Quantitative Tools for the Drug Transport Scientist
  2. Regulation of Organic Anion Transporters and the Clinical Implication
  3. Role of Transporters in Drug Exposure During Lactation
  4. Regulatory and Scientific Issues that Impact Development of Biotherapeutics

PROGRAM
Current Topics in Drug Metabolism and Pharmacokinetics

Biologics and Transporters – What’s New?

TIME

 

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

 

 

8:50 a.m.

Introductory Remarks

 

Dr. Robert M. Iannucci, Chair, NJDMDG

 

Johnson & Johnson, Raritan, NJ

 

 

9:00 a.m.

Imaging Techniques and Pharmacokinetic Modeling/Simulation: Useful Quantitative Tools for the Drug Transport Scientist

 

Dr. Kim Brouwer, Professor and Chair of the Division of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, and Professor, Curriculum in Toxicology, University of North Carolina [ slides ]

 

 

9:50 a.m.

Regulation of Organic Anion Transporters and the Clinical Implication

 

Dr. Guofeng You, Professor in the Department of Pharmaceutics, the Ernest Mario School of Pharmacy, Rutgers University [ slides ]

 

 

10:45 a.m.

Vendor Exhibit and Coffee Break

 

 

11:15 a.m.

Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling of Biologics

Dr. Donald E. Mager, Professor, Pharmaceutical Sciences, University at Buffalo, State University of New York

 

 

12:00 Noon

Lunch and Vendor Exhibit

 

 

1:30 p.m.

Role of Transporters in Drug Exposure During Lactation

 

Dr. Patrick McNamara, Professor and Chair of the Department of Pharmaceutical Sciences, School of Pharmacy, University of  Kentucky [ slides ]

 

 

2:15 p.m.

Vendor Exhibit and Coffee Break

 

 

2:45 p.m.

Regulatory and Scientific Issues that Impact Development of Biotherapeutics

 

Dr. Peter Thomas, Senior Program Manager, Early Development, Covance Laboratories, Inc, Madison, WI [ slides ]

 

 

3:30 p.m.

Program Conclusion

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In addition to our annual Fall Symposium, we try to sponsor 1-2 smaller meetings or mini-symposia in the Spring and Summer.


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